Academic Clinical Trials Program (ACT)

Leukemia and Lymphoma Society (LLS)
LOI Due Date
Application Due Date
Brief Description

The Leukemia and Lymphoma Society (LLS) recognizes the scientific and clinical merit of research developed and conducted by independent investigators affiliated with academic institutions. Such investigator-initiated trials (IITs) play an important role in developing experimental agents to address unmet medical needs, expanding the use of approved therapeutics, and improving the use of novel treatment regimens in real-world clinical settings. To support this important aspect of research, LLS created the Academic Clinical Trials Program (ACT) in 2022-23, and now presents a second request for applications.

The LLS ACT initiative is a clinical trial award program designed to develop cutting edge treatments that will have meaningful impact for blood cancer patients. These awards will fund clinical trials, up to $1M USD over a period of up to three years.

LLS is seeking truly novel advances. The primary focus will be Phase 1 or 2 clinical trials with novel experimental agents. Repurposing of approved therapies into novel indications will also be considered. Investigators conducting existing trials and expansion of existing trials are welcome to apply. Investigation of corporate-owned assets is allowed. If a corporate asset is studied, a clear path to market must be obtained and demonstrated. Proposals may include correlative studies including but not limited to biomarker identification, mechanism of action studies, and/or patient selection characteristics.