The Samuel Waxman Cancer Research Foundation (SWCRF) and The Mark Foundation for Cancer Research are pleased to issue a joint Request for Applications (RFA) for collaborative projects to focus on Aging and Cancer. Projects must include collaborations between two laboratories with different but complementary expertise. Proposals must justify the partnership through synergistic scientific aims. Awards will provide $500,000 total over three years ($250,000 to each PI).
Examples of potential research topics to understand and prevent the rising incidence of cancer due to aging include, but are not limited to:
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Senolytics, anti-inflammatory agents, and specific targets to enhance healthy longevity and diminish cancer incidence
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Impact of the aged microenvironment on the immune system, tumor progression, therapy response, and recurrent disease
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Biomarkers to evaluate aging and cancer risk such as clonal hematopoiesis, epigenetics patterns, DNA repair, mutations, and telomeres
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Approaches to limit therapy-associated cancer in older individuals and to establish how aging affects the response to treatment for cancer