The FY21 MRP Discovery Award supports innovative, non-incremental, high-risk/potentially high-reward research that will provide new insights, paradigms, technologies, or applications in melanoma research. Studies supported by this award are expected to lay the groundwork for future avenues of scientific investigation regarding an important question for melanoma research and/or patient community. The proposed research project should include a well-formulated, testable hypothesis based on a sound scientific rationale and study design. Preliminary data are not required. If preliminary data is presented it will be evaluated for its support of the specific aims, objectives, and/or hypothesis.
Innovation is a key characteristic of this funding opportunity. Innovative research may introduce a new paradigm, look at existing problems from new perspectives, or exhibit other highly creative qualities. Research that represents an incremental advancement on previously published work is not considered innovative. The following list, although not all-inclusive, provides examples of research that is not innovative:
- Using a published series of in vitro assays to further characterize a model system
- Incorporating known biomarkers into in vivo or clinical models of the disease or condition
- Investigating the next logical step or continuation of a previous research project
- Proposing work that is an incremental advancement of published data
Inclusion of preliminary data is not required, but is allowed. The strength of the proposed research should be based on sound scientific rationale and logical reasoning. The presentation of substantial preliminary data suggests that the proposed research project would be more appropriately submitted to a different award mechanism. The outcome of research supported by this award should be the generation of robust preliminary data that can be used as a foundation for future research projects. Absence of preliminary data will not negatively affect scientific peer or programmatic review of the application. All data presented will be subject to evaluation.
Early career investigators, including postdoctoral fellows (or equivalent), are encouraged to be named by the organization as the Principal Investigator (PI) on the application.