The purpose of this Notice is to inform potential applicants of the special interest of the National Cancer Institute (NCI) in encouraging the submission of applications to either PAR-20-089 Biomedical Data Repository ( U24-Clinical Trial Not Allowed) or PAR-20-097 Biomedical Knowledgebase ( U24-Clinical Trial Not Allowed) FOAs, focused on the establishment of new, or continued development of established cancer data resources that use state-of-the-art and cost-effective technologies and approaches, and that are of high value to the broad cancer research community. This NOSI applies to applications for both data repositories and knowledgebases.
Research Objectives
For the purpose of this Notice, we use the term “resource” to encompass both data repositories and knowledgebases. Through this NOSI, NCI will support the development of resources that are clearly linked to broad use cases in cancer research. This NOSI seeks applications that focus on establishment of new or continued development of established cancer data resources that use state-of-the-art and cost-effective technologies and approaches.
Resources relevant to this NOSI should address cancer research topics that include, but are not limited to, the following:
- Fundamental biological process related to cancer such as cell growth, transformation, and metastasis;
- Population-level determinants of cancer occurrence and outcomes;
- Cancer care delivery and implementation science;
- Cancer prevention, early detection, and screening;
- Cancer diagnosis, prognosis, treatment response, and patient management;
- Assessment of new anticancer agents, radiation treatments, surgical methods; and
- Cancer health disparities.