Brief Description
We are looking for bifunctional small molecules that can inhibit target protein function through protein-protein interactions (PPI). We are also looking for a methodology for rationally designing such bifunctional compounds based on protein structural information. (It does not matter whether the target interaction is intracellular or extracellular.)
Funding is proposal dependent, with up to $ 150K for 12 month project with potential follow-on funding for 1 year.